The main goal of the study was to provide and contrast data on quality of life for families in Slovenia that have children with intellectual disabilities and developmental disabilities (IDD) and families that have children with intellectual disabilities and autism spectrum disorders (ASD). The sample comprised 25 families with children with IDD and 19 families with children with ASD selected from schools in several villages in Slovenia. The data were collected using the FQOLS‐2006. The data analysis exploring the relationship between the two study groups (IDD and ASD) using the six measurement dimensions (Importance, Attainment, Satisfaction, Opportunities, Initiative, Stability) showed the mean ratings for all six measurement dimensions were higher for the IDD group than for the ASD group, although both groups rated Importance quite highly. Within the nine domains examined, there were some differences between the two groups. For the two main outcome measures, Attainment and Satisfaction, the scores for Satisfaction were consistently higher for the IDD group than for the ASD group. A combination of qualitative and quantitative data revealed that two of the nine domains, Family Relationships and Community Interaction, appear to contribute positively to family quality of life for both groups in this sample, while family life relating to the other seven domains requires remediation. Data from this family quality of life study provides evidence to suggest to policy makers and service providers that there might be a substantial amount of work to be done in the future to provide appropriate and efficient support for families with children with disabilities, especially for those with ASD, so that these families can lead lives of quality.