In this article, I review youth‐led participatory action research (YPAR) as an innovative equity‐focused approach to promote adolescent health and well‐being. YPAR draws on the expertise of adolescents as they conduct research and improve conditions that support healthy development. Specifically, I explain the core principles and processes of YPAR, provide examples, discuss theoretical and empirical support for the effects of YPAR at many levels, and identify areas for research.