The gap between science park aspiration and accomplishment is conceptualized as ‘innovation incommensurability,’ the persisting dilemma of a physical structure oriented innovation mechanism. A typology of science park impetuses and growth–analyzing critical elements, goals/ends and paths/means–suggests an appropriate balance between ‘exogenous’ and ‘endogenous’ innovation strategies in various regional circumstances. Alternative strategies of science park development are a ‘strategic research site’ to evaluate the roles of a university–industry–government triple helix in developing the science park model. Innovation incommensurability can be overcome by a longer‐term endogenous strategy combined with significant public investment. Ambitious science park projects, which were either early failures or later lost support, may succeed once a triple helix base is built to achieve an innovation eco‐system.