Background A validated geographic search filter for the retrieval of research about the United Kingdom (UK) from bibliographic databases had not previously been published. Objectives To develop and validate a geographic search filter to retrieve research about the UK from OVID medline with high recall and precision. Methods Three gold standard sets of references were generated using the relative recall method. The sets contained references to studies about the UK which had informed National Institute for Health and Care Excellence (NICE) guidance. The first and second sets were used to develop and refine the medline UK filter. The third set was used to validate the filter. Recall, precision and number‐needed‐to‐read (NNR) were calculated using a case study. Results The validated medline UK filter demonstrated 87.6% relative recall against the third gold standard set. In the case study, the medline UK filter demonstrated 100% recall, 11.4% precision and a NNR of nine. Conclusion A validated geographic search filter to retrieve research about the UK with high recall and precision has been developed. The medline UK filter can be applied to systematic literature searches in OVID medline for topics with a UK focus.