--- - |2+ Abstract Objective Mixed methods can foster depth and breadth in psychological research. However, its use remains in development in psychotherapy research. Our purpose was to review the use of mixed methods in psychotherapy research. Method Thirty‐one studies were identified via the PRISMA systematic review method. Using Creswell & Plano Clark's typologies to identify design characteristics, we assessed each study for rigor and how each used mixed methods. Results Key features of mixed methods designs and these common patterns were identified: (a) integration of clients’ perceptions via mixing; (b) understanding group psychotherapy; (c) integrating methods with cases and small samples; (d) analyzing clinical data as qualitative data; and (e) exploring cultural identities in psychotherapy through mixed methods. Conclusion The review is discussed with respect to the value of integrating multiple data in single studies to enhance psychotherapy research. - Journal of Clinical Psychology, EarlyView.