--- - |2 Abstract There have been several attempts to reduce data scattering in contractility studies. When using superfused muscle preparations for contractility experiments, there is always the question how to compensate for variabilities in muscle thickness. A simple but rather imperfect approach is the normalization of force to cross‐sectional area. However, this attempt does not consider the possibility of hypoxic cores in thick muscles, which probably do not really contribute to force development. Han et al. recently published a new computer model to investigate the relevance of oxygen distribution for force generation when intact muscles are superfused, as frequently used in physiological experiments. This article is protected by copyright. All rights reserved. - Acta Physiologica, Volume 0, Issue ja, -Not available-.