We analysed bone remains of camelids from the Maquijata site, assigned to the late pottery‐making and farming stage (ca. 800–400 BP), in order to differentiate between domestic and wild species in the Chaco‐Santiago archaeological region. This region is considered marginal to the Argentine Northwest regarding its cultural development and has received less attention than other regions. South American camelids have been one of the major resources in this continent, with domestication recorded in the South Central Andes at around 4400–3000 BP. We applied osteometric techniques and multivariate statistical analyses to proximal phalanges; the results showed interspecific differentiation of archaeological specimens, though with some methodological application issues. These results are the first contribution regarding the presence of domesticated animals in the study area. Copyright © 2012 John Wiley & Sons, Ltd.