Agricultural economics is at the nexus of the major policy options surrounding the global bio‐economy. The outputs from agriculture have expanded beyond the traditional food, feed, and fiber to include fuel and other nonfood applications as well as environmental goods due to recent technological developments and changing consumer demands. Numerous policy questions have arisen within the bio‐economy. This article introduces and summarizes several invited panel sessions on issues of special importance in the global bio‐economy: new institutions of dealing with uncertainty and increased volatility related to climate change; structural transformations in agricultural production and food consumption and their effect on development; biofuel policies and development; and determinants of changes in consumer attitudes to new products and technologies.