The objective of this study is to conduct a network analysis of the air and train connections between selected cities in Central and Eastern Europe in the context of business tourism. The selected cities are key destinations for the meeting industry in this part of Europe. The study was initiated due to the huge significance of business travel for these cities. The authors of this paper analysed the interconnections between these cities and identified the leaders of the industry in the region. This paper is also based on a case study approach and analysis relating to the cities. Copyright © 2012 John Wiley & Sons, Ltd.