This inaugural virtual issue of the Health Information and Libraries Journal (HILJ) celebrates the contribution of health information in informing health and social care library and information provision. It has been drawn together to reflect the 2010 biennial Health Libraries Group conference theme of Keeping Information Centre Stage Amid Changing Scenery and includes a series of eleven key papers published in the journal over the last two years. This virtual issue mirrors the usual format of a journal issue with a review article, original articles and regular features on Learning and Teaching in Action, Using Evidence in Practice and International Perspectives and Initiatives. All papers included in this virtual issue of Health Information and Libraries Journal are available free online.