Successful adoption and use of information systems is an area of continued research in the field of information systems. This prior research has shown that how we adopt and use an information system depends on how we make sense of it. The sense‐making activity is carried out through our cognitive structures of knowledge that relate to technology (our technological frames). The sense‐making activity changes over time, as use and exposure to differing technologies occur. Most research into information systems in organisations has focused on a specific information system; this preoccupation with studying discrete projects at one point in time may be limiting. In an attempt to fill this research gap, we use the socio‐cognitive perspective of Orlikowski & Gash to analyse technological frames in one organisation over a longitudinal period to evaluate sensemaking in relation to multiple systems. The interpretive case study looks at the technological frames of senior management, faculty teaching staff, information technology (IT) mediating staff and IT groups over a 10‐year period in a university and finds that there were incongruent frames between senior management and other groups within the organisation with senior management holding a dominant frame. The consequences of these frames were demonstrated when they were linked to the use of the four major information systems in the organisation, showing repeated historical patterns of use that caused inefficiencies due to the incongruent frames of the various groups. The unchanging dominant technological frame contributed to this pattern.