Problem solving is a key component of weight loss programs. The Social Problem Solving Inventory–Revised (SPSI-R) has not been evaluated in weight loss studies. The purpose of this study was to evaluate the psychometrics of the SPSI-R. Cronbach’s α (.95 for total score; .67-.92 for subscales) confirmed internal consistency reliability. The SPSI-R score was significantly associated (ps < .05) with decreased eating barriers and binge eating, increased self-efficacy in following a cholesterol-lowering diet, consumption of fewer calories and fat grams, more frequent exercise, lower psychological distress, and higher mental quality of life; all suggesting concurrent validity with other instruments used in weight loss studies. However, confirmatory factor analysis of the hypothesized five-factor structure did not fit the data well (² = 350, p < .001).