Research on orchestral musicians has predominantly used survey methods to measure stress and/or work satisfaction; studies have seldom used in-depth interviews to ask orchestral musicians to reflect on their own practice and have neglected to elicit musicians’ perceptions of the processes involved in expert orchestral performance. Using semi-structured interviews, this research aimed to investigate 20 musicians’ experiences of working in a major London orchestra, focusing in particular on the skills and qualities they feel are required, and on how they negotiate challenges and sustain their careers. The interviews were analysed thematically using a grounded theory approach. The sample emphasized a set of skills which they considered vital for achieving excellence in the orchestral context, encompassing listening to, communicating with, and adapting to those around them at all times during rehearsal and performance. Strong social and interpersonal skills were also cited as important for orchestral work, with participants stressing the significance of maintaining good social relationships with colleagues in order to foster a conducive environment to achieving excellence on stage. These findings are considered in light of their potential implications for conservatoire training and their contribution to research on co-performer communication and collaboration.