An increasing number of students with Asperger’s syndrome are entering college today. Students with Asperger’s syndrome face complex symptomology such as difficulty with social skills, narrowed interests, sensory issues, and lack of self-awareness that may affect their ability to complete college and successfully enter the workforce. Career counselors could apply social cognitive career theory as an effective intervention when working with college students diagnosed with Asperger’s syndrome. A case illustration is presented as an example.