The purpose of the study was to develop a Short-Form Chinese version of the Health and Safety Executive’s Management Standards Indicator Tool that can be used to measure work-related stress among nurses in Taiwan. Three subscales (supportive climate, role perception, and workload) were developed from an exploratory factor analysis. The three-factor confirmatory factor analysis indicated that the model fit the data well. The evidence based on convergent validity was supported by a significant correlation between the Short-Form Chinese version of the Health and Safety Executive’s Management Standards Indicator Tool and the job satisfaction subscale of the Chinese Patient Safety Attitude Questionnaire. Cronbach’s α values demonstrated internal item consistency for the Short-Form Chinese version of the Health and Safety Executive’s Management Standards Indicator Tool.