The "real scientist" brings not only investigative ingenuity but also courage and integrity that permit a challenging of the status quo. Here, three issues and their relationship are considered: (a) Taboo Topics as per Norman Farberow’s 1963 book, where conscious/unconscious fears and prohibitions can hinder scientific progress, (b) creative qualities catalyzing open-mindedness and pursuit of truth, and (c) factors heightening or lowering resistance to paradigm shift as per Thomas Kuhn—including sudden change when the data become overwhelming. A key illustration involves parapsychology and the work of Stanley Krippner and colleagues—showing long-standing and rigorous research, plus efforts to disseminate findings and to open minds.