This article responds to Truth Default Theory (TDT) and Information Manipulation Theory II (IMT2). First, I discuss assumptions made by previous research on deception that TDT or IMT2 question. For example, TDT questions the assumption that nonverbal behaviors are important for detecting deception, and IMT2 questions the assumption that deception requires additional cognitive effort. Given TDT’s emphasis on context, I note that additional research is needed to identify antecedents of truth and lies. Furthermore, more research is needed to identify the characteristics of transparent liars. One suggestion is to integrate transparent liar research with IMT2’s proposition IM6. Further suggestions are offered about integrating research on prolific liars with IMT2 and integrating research on cognitive load and deception with IMT2.