This study analyses the contribution of holiday trips to the levels of life satisfaction reported by individuals with and without disability by using an approach in which life satisfaction is seen as a combination of various life satisfaction domains (health, job, housework, household income, dwelling, and leisure). Using longitudinal data from the German Socio-Economic Panel, we estimate a two-layer model which proposes that satisfaction with different domains of life are interrelated and wherein life satisfaction depends on the weight that the individual allocates to each of these domains. The results show that disabled people who participate in holiday trips obtain higher levels of satisfaction with health, job, and housework than do nondisabled ones, especially when this participation is more intense. In addition, satisfaction with health and household income has a significant effect on the overall life satisfaction reported by disabled individuals. Public policy recommendations are given.