The objective is to explore the relationship between passive smoking and female breast cancer using meta-analysis. Literature on risk factors for female breast cancer published from January 2001 to December 2011 was collected from CBM, CAJD, VIP, WanFangData, and MEDLINE databases. The meta-analysis was performed using Review Manager 5.0.24. A total of 8 studies were included according to inclusion and exclusion standards. The results of the meta-analysis indicated that the combined odds ratio (OR) estimate for those who had been exposed to passive smoke from tobacco was 1.67 (95% confidence interval [CI] = 1.27-2.21). Results of the subgroup analysis were consistent with an OR = 1.98 (95% CI = 1.63-2.42) for 1:1 paired design research and 1.60 (95% CI = 1.08-2.37) for the group design research. Results suggest a possible association between passive tobacco smoke and female breast cancer in China.