This paper presents vibration control of a mixed-mode magnetorheological fluid-based mount system using a new robust fuzzy sliding mode controller. A novel model of controller is built based on adaptive hybrid control of interval type 2 fuzzy controller incorporating with a new modified sliding mode control. The interval type 2 fuzzy is optimized for computational cost by using enhanced iterative algorithm with stop condition, and a new modified switching surface of sliding mode control is designed for preventing the chattering of the system. The controller is then experimentally implemented under uncertain conditions in order to evaluate robust vibration control performance. In addition, in order to demonstrate the effectiveness of the proposed controller, two fuzzy sliding mode control algorithms proposed by Huang and Chan are adopted and modified. The principal control parameters of three controllers are updated online by adaptation laws to meet requirements of magnetorheological mount system which has two operation modes: flow mode and shear mode. It is shown from experimental realization of three controllers that the proposed control strategy performs the best under uncertain conditions compared with two other modified controllers. This merit is verified by presenting vibration control performances in both time and frequency domains.