Big-end bearing knock is considered to be one of the common mechanical faults in internal combustion engines (IC engines). In this paper, a model has been built to simulate the effects of oversized clearance in the big-end bearing of an engine. In order to find a relationship between the acceleration response signal and the oversized clearance, the kinematic/kinetic and lubrication characteristics of the big ending bearing were studied. By adjusting the clearance, the impact forces with different levels of bearing knock fault can be simulated. The acceleration on the surface of the engine block was calculated by multiplying the simulated force spectrum by an experimentally measured frequency response function (FRF) in the frequency domain (and then inverse transforming to the time domain). As for experimentally measured vibration signals from bearing knock faults, the signal processing approach used involved calculating the squared envelopes of the simulated acceleration signals. The comparison to the experimental results demonstrated that the simulation model can correctly simulate vibration signals with different stages of bearing knock faults.