Recent research on psychosocial interventions addressing the well-being of women with HIV/AIDS has brought new options for practitioners. This study critically reviews the treatment features, methodological quality, and efficacy of these interventions.

A comprehensive search between 2000 and 2011 identified 19 studies employing 10 different interventions.

In all, 11 studies were methodologically strong and 12 reported interventions superior to other treatments. Among those with positive results, Cohen’s effect sizes ranged from small (d = 0.33) to large (d = 1.50) across well-being outcomes. The Cognitive Behavioral Stress Management/Expressive Supportive and Structural Ecosystems Therapies ranked as probably efficacious. The Teaching, Raising and Communicating with Kids and the Maternal HIV Self-Care Symptom Management programs were ranked as promising treatments.