Interaction facilitated by social media is becoming an integral part of life in contemporary society, tweaking the human psyche's deep need to connect. Having changed the creation, sharing, and consumption of information, it must be inevitably integrated into the operation of most human organizations. While some organizations readily adapt themselves to social media, the majority have struggled. This special issue of the Social Science Computer Review investigates different aspects of social media use in government, nonprofit, education, and health care organizations.