The aim of this study was to test a theoretical model of depression for Black single mothers. Participants were 208 Black single mothers, aged 18 to 45, recruited from community settings. The a priori over-identified recursive theoretical model was tested via the LISREL 9.1 program using a maximum likelihood estimation for structural equation modeling. The chi-square indicated that there was an excellent fit of the model with the data, ²(1, N = 208) = .05, p = .82. The fit indices for the model were excellent. Path coefficients were statistically significant for seven out of eight of the direct paths within the model (p < .05). The two indirect paths were also statistically significant. The theory was supported and can be applied by health care professionals when working with depressed Black single mothers.