Aims To examine the associations between alcohol control policies in four regulatory domains with alcohol consumption in low‐ and middle‐income countries (LAMICs), controlling for country‐level living standards and drinking patterns. Design Cross‐sectional analyses of individual‐level alcohol consumption survey data and country‐level alcohol policies using multi‐level modeling Setting Data from 15 LAMICs collected in the Gender, Alcohol, and Culture: an International Study (GENACIS) Participants Persons aged 18‐65 Measurements Alcohol policy data compiled by the World Health Organization; individual‐level current drinking status, usual quantity and frequency of drinking, binge drinking frequency, and total drinking volume; Gross Domestic Product based on purchasing power parity (GDP‐PPP) per capita; detrimental drinking pattern scale; and age and gender as individual‐level covariates Findings Alcohol policies regulating the physical availability of alcohol, particularly those concerning business hours or involving a licensing system for off‐premises alcohol retail sales, as well as minimum legal drinking age, were the most consistent predictors of alcohol consumption. Aggregate relative alcohol price levels were inversely associated with all drinking variables (p<.05) except drinking volume. Greater restrictions on alcohol advertising, particularly beer advertising, were inversely associated with alcohol consumption (p<.05). Policies that set legal blood alcohol concentration (BAC) limits for drivers and random breath testing to enforce BAC limits were not significantly associated with alcohol consumption. Conclusions Alcohol policies that regulate the physical availability of alcohol are associated with lower alcohol consumption in low‐ and middle‐income countries.