Objective: Many college students have a history of interpersonal violence (IPV) and are thus at risk of greater mental health problems. This study evaluated the efficacy of a web-based stress management program targeting the established protective factor of present control in promoting well-being among students with and without a history of IPV. Method: Students from an introductory psychology course were randomly assigned in a 2:1 ratio to the web-based stress management intervention (n = 329) or the waitlist comparison group (n = 171). Self-report measures of 4 outcomes (perceived stress, symptoms of depression, anxiety, and stress) and 2 mediators of intervention efficacy (present control, rumination) were completed online pre- and postintervention. IPV history was assessed preintervention. Results: Thirty-nine percent reported an IPV history. The intervention group reported less distress than the comparison group at posttest but effects were larger in the IPV group (mean d = .44) than in the no IPV group (mean d = .10). Increases in present control mediated intervention effects in both groups; decreases in rumination mediated intervention effects in the IPV group only. Conclusions: Web-based universal prevention stress management programs may be a cost-effective way to teach protective skills to students with an IPV history. (PsycINFO Database Record (c) 2015 APA, all rights reserved)