This article explores the psychoanalytic construct of annihilation anxiety in order to develop a more thoroughgoing engagement between criminological theory and contemporary psychoanalysis. Though a few criminologists have commented on crime, scapegoating and retribution using classic psychoanalytic ideas, we bring Hurvich’s current empirical work on annihilation anxiety to the discourse. Beginning with his definition of annihilation anxiety as ‘fears of being overwhelmed, merged, penetrated, fragmented, and destroyed’, we apply Hurvich’s measures to reactions to crime and insecurity and interpersonal, collective and international crime. We discuss doing criminology interpretively, applied to the dynamic connections between crime and reactions to it, including political and policy responses. We conclude that criminologists could and should help distinguish between potential and imminent threats, to advance a post-positivist approach to crime and other security threats. We argue that such an approach moves criminology toward a social science more humane and pragmatic for its conscious engagement with unconscious fears harboured amidst the purportedly rational calculi of justice.