This article examines the relationship between sexual orientation and religious experience of men from early adolescence to adulthood. Data have been obtained from an online survey of 1,042 males who were part of a larger sample of lesbian, gay, bisexual, transgender, and queer/questioning (LGBTQ) persons who are current or former members of the Church of Jesus Christ of Latter‐Day Saints (LDS, Mormon). While early religious experience was essentially identical to that of heterosexuals, the gap between religious norms and experience widened as these men moved through early and mid‐adulthood. Those who married did so at a later age, and experienced a high rate of divorce. Continued participation, integration, and conformity to LDS ideals was not attributable to faith in, or a departure from, fundamental doctrinal belief. Instead, the responsible variable was sexual orientation, measured by the Kinsey Scale scores across behavior, attraction, and identity. For those near the exclusively homosexual end of the spectrum, the failure to change sexual orientation after intense effort over many years resulted in loss of belonging, belief, and participation, along with increased negative emotions and a sense of mistreatment.