The Pharmaceutical Society of Great Britain was established in 1841 to represent the interests of its members, many of whom were small chemist and druggist retailers. Throughout the century this institution attempted to influence new policies designed to control the sale of poisonous substances routinely held by these shopkeepers. Using its in-house publication, the Pharmaceutical Journal, the Society argued for recognition of chemists and druggists as experts in the storage and distribution of poisons. This article examines the discursive strategy adopted by the Pharmaceutical Society in its attempts to retain control over the sale of chemicals. Its activities are analysed both in respect to the complex and socially embedded nature of chemical products, and to the technocratic nature of its claims.