The Career Adapt-Abilities Scale (CAAS) has become one of the most widely used questionnaires to assess career adaptability. To facilitate its integration into large surveys, in varied settings, the aim of this article was to develop a brief 12-item version, the Career Adapt-Abilities Scale–Short Form (CAAS-SF). A sample of 2,800 French- and German-speaking adults living in Switzerland completed the CAAS. On a first random subsample, a principal component analyses conducted on the CAAS-SF suggested a four-factor solution. A one-to-one association was found between these components and the subscales of the CAAS-SF. Confirmatory factor analyses, conducted on a second random subsample, confirmed the hierarchical factor structure of this short version. Based on Cheung and Rensvold’s criteria, the CAAS-SF reached measurement equivalence across linguistic and gender groups. Furthermore, the 12- and 24-item versions were strongly associated. The results supported the CAAS-SF as pertinent and economical alternative to the 24-item version.