This is a first initiative to apply career exploration research to understand and assess a career intervention in Hong Kong. In responding to educational and social changes, a one-semester academic career course was designed to foster the participants’ career exploration in a public university in Hong Kong. Data were drawn from about 380 students enrolled voluntarily across three successive semesters in either the career course or another academic course unrelated to career development. The career course served as an intervention to enhance exploration for enrolled students, with students from an unrelated academic course in the same semester included as a comparison group. Pre- and post-assessments were conducted to assess the career course’s impact in terms of career decision making, career adaptability, and relational support. The reflection and discussion here focus on the course’s effectiveness and cultural appropriateness as a career intervention tool and its strategic value in higher education in Hong Kong and beyond.