This article reflects on the merits of the expedition as an anthropological method on the basis of a recent cross-disciplinary experience, involving biologists, archaeologists and anthropologists working together in High Arctic Greenland. True to the term, the expedition had chartered a vessel from where the team could go ashore in places that would otherwise have been difficult to access, and where the individual perspectives could cross-fertilize each other in actual practice. It is argued that anthropology itself is a mode of experimentation in practice, which enables new trains of thought, and an engagement with other disciplinary practices. The gain of our cross-disciplinary experiment was therefore not only to know more about the makings of a particular landscape in a multi-disciplinary perspective, but also to understand how anthropology makes sense of inherently moving facts.