Background It has been stated that care for children with chronic health conditions tends to focus on condition‐specific issues rather than how these children experience their health and everyday life functioning. Aim The aim of this study was to explore children's experiences about a structured assessment of health‐related quality of life applied during a patient encounter. Methods Prior to the start of the study, a clinical intervention based on the questionnaire DISABKIDS Chronic Generic Measure (DCGM‐37) was performed. A qualitative explorative design was chosen, and 25 children between 10–17 years of age were interviewed after the consultation at four different paediatric outpatient clinics. Data were analysed according to qualitative content analysis. Results The results were twofold: children experienced that the assessment was providing them with insights about their health, which motivated them to make lifestyle changes. When outcomes were discussed and requested, the children felt encouraged. Conclusions The use of an assessment of health‐related quality of life may promote insights about health and encourage children with chronic health conditions to discuss their outcomes with healthcare professionals.