This study theorized the relationship among information exposure, affect, cognition, and behavioral intention by constructing a comprehensive model that combines an integrative model, media effects studies, and the risk-as-feelings hypothesis. Specifically, in the cancer context, we examined how exposure to information is associated with affect and cognition, which influence behavioral intention. A two-wave survey about stomach cancer was conducted among Korean people aged 40 or older (n = 1,130 at Wave 1 and 813 at Wave 2). Exposure to cancer information was positively associated with affective (cancer fear), affective-cognitive (cancer worry), and cognitive (risk perception) conditions at Wave 1, which predicted screening intention at Wave 2. However, cancer fear reduced screening intention, unlike cancer worry and cancer risk perception, which increased screening intention. While cancer risk perception influenced screening intention indirectly through norm, cancer fear and cancer worry had a direct impact on screening intention.