A self-report instrument assessing work-related factors among people with psychiatric disabilities would be useful when trying to match possible employment or prevocational opportunities with people’s desires and capacities. The aim of this study was to explore the factor structure, internal consistency, and construct and criterion validity of the Worker Role Self-Assessment (WRS) in this group as well as possible floor and ceiling effects. The participants were 283 clients from day centers for people with psychiatric disabilities and from outpatient units for people with psychosis. They completed the WRS and instruments selected to assess construct validity in terms of convergent (motivation for work and current activity level as reference variables) and discriminant validity (quality of life and self-rated health as reference variables). Two factors were identified, one tapping beliefs in a future worker role and one reflecting current capacities and routines. The internal consistency for the scale as a whole was good at 0.84. The factor reflecting a future worker role correlated as expected with the reference variables used to assess convergent and discriminant validity, whereas current capacities and routines showed a moderate association with quality of life and self-rated health, assumed to indicate discriminant validity. Criterion validity was shown in that those who had recent work experiences scored higher than the others on WRS. No floor or ceiling effects were identified. The findings indicate acceptable psychometric properties of the WRS. Further development is still warranted, however; the factor solution needs to be replicated and the construct validity should be further established.