The article addresses the shifting patterns of atypical employment across the regions of Greece, severely hit by the 2009 crisis. Changes are depicted by NUTS-II level data for the pre- and post-crisis periods of 2005–2009 and 2009–2011. A regional categorization is suggested, as different forms of atypical employment, namely part-time, temporary, solo self-employment and family work, have expanded unevenly across space. The authors argue that different patterns are related to regional specialization and industrial structures differently affected by the crisis. Established forms of atypical employment have been shaken, while new highly precarious ones have been boosted. Moreover, regulatory reforms for higher labour flexibilization have also defined the emergent atypical employment patterns in Greece. The article points out that in the Greek labour market, already marked by high flexibility and poor job security and social benefits, recent regulatory reforms increasing flexibilization have deteriorated labour and devalued atypical employment.