Previous studies have documented Black churches’ receptivity to implementing adolescent sexual health programs within their congregations. Some authors have argued for new sexual health programs to be designed specifically for churches, similar to the development of school- and community-based interventions. However, strategies and curricula used in secular settings may also be effective in influencing sexual behaviors among youth in churches. The current study examined the ways in which the phases of two theorized intervention adaptation frameworks were reflected in the desired key components of a church-based sexual health program. Participants in this community-based participatory research project were youth, parents, and faith leaders from nine Black churches in Baltimore, Maryland. Our findings suggest that the priorities of church stakeholders are consistent, rather than discordant, with the current paradigms of evidence-based sexual health programs and intervention adaptation. Future research and practical implications are discussed.