An important element of contemporary social work is the influence of international trends on the contexts of practice. In this article, we will critically examine aspects of globalisation and the relationships between health inequalities and social inequalities and the implications for social work practice. Giles called on social workers to develop a ‘health equality imagination’; however, the challenge for practitioners on a day-to-day basis is how to integrate such an imagination into their work. A number of suggested approaches towards a greater engagement in addressing health inequalities in social work practice, education and research are also presented.