This article presents the responses from frontline social work practitioners, administrators and educators in Trinidad to the recently published Global Agenda for Social Work and Social Development. In acknowledging the significance of the Global Agenda, it became apparent that there was a need to solicit and channel the views of the local practitioners on this declaration. This article is based on a study carried out by the social work unit of the University of the West Indies. The study was intended to facilitate the articulation of the perceptions of key constituents about the Global Agenda and to critically analyse and respond to the Global Agenda within the context of a developing region. This article draws on the data that were collected from a focus group discussion among key constituents in the profession of social work in Trinidad. The findings support the Global Agenda as culturally relevant to the social realities facing Trinidad and Tobago and the Caribbean region at this time. The prevailing view was that notwithstanding the responsibility to institutionalise the currency of the profession to influence social policy development on critical human rights and social justice issues, country-specific mandates and jurisdictions must be maintained as the primary determinants of social work practice, education and policy development. The potential value, applicability and advancement of the four commitments put forward in the Global Agenda are also highlighted.