Previous research suggests that prisoners have a higher rate of disability than non-institutionalized adults. This study used nationally representative data to update the prevalence rate, identify correlates of disability, and evaluate disability-related disparities in use of prison-based educational services, vocational programs, and work assignments. Data were obtained from 18,185 prisoners interviewed in the 2004 Survey of Inmates in State and Federal Correctional Facilities. Survey logistic regression procedures were conducted using Stata 13. Disability prevalence remained substantially higher among prisoners than among the non-institutionalized population. Prisoners were more likely to report specific learning, sensory, and speech-related disabilities than non-institutionalized adults. Prisoners with at least one type of disability had more criminogenic risk factors and come from a more disadvantaged background than prisoners without disability. Prisoners with disabilities were also less likely to utilize vocational programs and work assignments but were more likely to use educational programs than prisoners without disabilities. In summary, 41% of prisoners reported a disability, most commonly, learning disabilities. Prisoners with disabilities were identified as an at-risk group for recidivism, given their pre-incarceration experiences, and limited vocational and work-related training received in prison.