The Asia-Pacific region is a hot spot for population and tourism growth, both key drivers of water demand. Already, more than 75% of countries in this region are experiencing water stress. The management of water is becoming increasingly pressing, including for the tourism industry. Yet there has been little research into the predictors of water use in tourism in the Asia-Pacific region and opportunities for water saving. Therefore, this article develops both total and per guest night water-use models to determine the drivers of water use in accommodation in the Asia-Pacific region, delves into the differences between regions, and assesses the effectiveness of different water-saving measures. The results suggest geographical differences in water use that are influenced by climate zone and pool facilities. Importantly, the per guest night water-use model indicates that there are economies of scale to water use and that low/dual-flush toilets can significantly conserve water.