The purpose of this study was to explore the role of nonspousal family support on mental health among older, church-going African American men. The mixed methods objective was to employ a design that used existing qualitative and quantitative data to explore the interpretive context within which social and cultural experiences occur. Qualitative data (n = 21) were used to build a conceptual model that was tested using quantitative data (n = 401). Confirmatory factor analysis indicated an inverse association between nonspousal family support and distress. The comparative fit index, Tucker–Lewis fit index, and root mean square error of approximation indicated good model fit. This study offers unique methodological approaches to using existing, complementary data sources to understand the health of African American men.