This article integrates the company operations decisions (i.e. location, production, inventory, distribution, and transportation) and finance decisions (i.e. cash, accounts payable and receivable, debt, securities, payment delays, and discounts) in which the demands and return rate are uncertain, defined by a set of scenarios. The cash flow and budgeting model will be coupled with supply chain network design using a mixed integer linear programming formulation. The article evaluates two financial criteria, that is, the change in equity and the profit as objective functions. The results indicate that objective functions are partially interdependent, that is, they conflict in certain parts. This fact illustrates the inadequacy of treating process operations and finances in isolated environments and pursuing objective myopic performance indicators such as profit or cost. Due to the importance of the supply chain network design problem, a multi-objective robust optimization with the max–min version is extended to cope with the uncertainty. A solution approach integrating Benders’ decomposition method with the scenario relaxation algorithm is also proposed in this research. The improved algorithm has been applied to solve a number of numerical experiments. All results illustrate significant improvement in computation time of the improved algorithm over existing approaches. For a problem, the proposed algorithm shows a significant reduction in computational time compared with the Benders’ decomposition and scenario relaxation that shows the efficiency of the proposed solution method.