Titanium alloys generally show low machinability ratings. They are referred as difficult-to-cut materials due to their inherent properties such as low thermal conductivity, high chemical reactivity and high strength at elevated temperatures. Cooling strategies play an important role to improve the machining performance of the cutting process. In order to facilitate the heat dissipation from the cutting zone, generous amount of coolant is used when machining highly reactive metals such as titanium alloys. Generally, cutting coolants are nominated as pollutants due to their non-biodegradable nature. This article presents experimental evaluation of a minimal quantity cooling lubrication system. The study investigates a combination of sub-zero-temperature air and vegetable oil–based mist as possible environmentally benign alternative to conventional cooling methods. The results are compared with the dry and flood cutting environments as well. Machinability was evaluated experimentally by considering the surface finish, cutting forces, tool life and their associated tool wear mechanisms. It was concluded from the results obtained from the surface roughness, cutting force and tool life investigation that minimal quantity cooling lubrication (internal) cooling strategy has encouraging potential to replace the conventional flood cooling method.