Accommodating students with disabilities may influence their academic performance. This study investigates the effects of accommodations on grade point average (GPA) by examining a sample of 1,248 students from the Office of Disability Services at the Pennsylvania State University. The results showed the significant influence that both test accommodation, specifically extension of time and modification of materials, and course accommodation, specifically assignment accommodation, had on overall GPA while controlling demographic variables and types of disability. The authors also discuss the significance, limitations, and implications of such results.