This article examines the history of the development of drone technology to understand the longer histories of surveillance and targeting that shape contemporary drone warfare. Drawing on archival research, the article focuses on three periods in the history of the drone: the early years during World Wars I and II, the Cold War, and the 1990s. The history of the drone reveals two key trends in Western warfare: the increasing importance of intelligence, surveillance, and reconnaissance (ISR) and the development of dynamic targeting. These trends converge today in a practice of lethal surveillance where ISR capabilities are directly linked to targeted killing, effectively merging mechanisms of surveillance and knowledge production with decisions on life and death. Taking this history of lethal surveillance into account not only reframes current debates on drone warfare, but also connects the drone to other practices of security and control.