This paper presents an analytical–synthetic model of ergonomic research of the abilities of the dispatcher/operator in the control room for the automatic control of railway transportation. Twenty performance indicators describing the operators’ performance (work capacity and perceptive abilities) and the main characteristics of the control room (work organization and ergo-technical analysis) are identified. A group fuzzy analytic hierarchy process is applied in the process of ranking and selection of key performance indicators of railway control rooms. The selected key performance indicators (the operator’s hand movement, visual symptoms of fatigue, device error analysis, location and dimensions of the control desk) are analysed in detail.