Politicians and leaders use metaphors and frames in political communication to provide citizens with meaning, persuade, and promote emotional reactions. At the same time, a large body of scholarship documents the propensity for female leaders to "speak in a different voice" when in political office. Research to date on policy metaphors, however, rarely compares male and female leaders’ use of metaphors or evaluates the use of these metaphors in local politics. Using State of the City addresses from 16 cities to evaluate the connection between policy agendas, metaphors, and mayoral gender, I find that male and female leaders emphasize similar issues in their speeches, but use different frames to present these issues, with female leaders using more nurturing framing than do male leaders. In addition, while both male and female mayors emphasize economic development as the central issue in their speeches, female mayors use more inclusive framing in these discussions.