Equid remains are scarce and very fragmented in Iberian Neolithic and Bronze Age sites. Evidence suggesting that horses were domesticated does exist, but it is often inconclusive, thus leaving the question unanswered. Today, DNA analyses have provided information about a, most likely Iberian, nucleus of horse domestication, making it crucially important to expand the database. The Holocene sequence (6th and 3rd millennium cal bc) of the Cueva de El Mirador (Sierra de Atapuerca, Spain) has yielded 92 equid remains distributed in 12 Neolithic and Bronze Age levels. In this paper, we present the study of the equid remains from the Cueva de El Mirador from an archaeozoological perspective, giving indirect evidence of horse domestication. Our results vary widely and lead to open interpretations about horse domestication and how humans used these animals. This study of horse remains focuses on species identification and on determining how humans economically used these animals. Copyright © 2014 John Wiley & Sons, Ltd.