This paper reports upon the learning that emerged from a development project which aimed to facilitate improvements in multiagency work in domestic abuse and safeguarding children. The two‐year project (2011–13), funded by the Department for Education and led by WomenCentre, a specialist voluntary sector organisation based in West Yorkshire, was undertaken in nine local authorities in the north of England. Activities undertaken during the project included case mapping, service user and professional engagement exercises, observation of local multiagency meetings and provision of training. An evaluative research study examined the work of the project and the learning that emerged. Drawing upon data from telephone interviews with project participants, analysis of case mapping and project reports, this paper discusses some critical issues which emerged from this project. The paper draws attention to the different understandings and priorities which shape interprofessional practice in relation to safeguarding children and domestic abuse, and the complexities of the wider interagency environment including coordination, resources and expertise. Recommendations for improving multiagency work to achieve better outcomes for women and children experiencing domestic abuse are discussed. Copyright © 2015 John Wiley & Sons, Ltd. ‘An evaluative research study examined the work of the project and the learning that emerged’ Key Practitioner Messages Multiagency working in domestic abuse and safeguarding children is complex and could be improved. The impact of professional differences in how cases are understood and managed, particularly in relation to ‘risk’, as well as different professional priorities and approaches to working with families should be recognised and considered within the multiagency context. Practitioners may want to consider whether ‘case mapping’ is pertinent to their own safeguarding practices and processes. ‘Multiagency working in domestic abuse and safeguarding children is complex and could be improved’